Preimplantation Genetic Diagnosis, PGD

An advanced IVF lab technique called Preimplantation Genetic Diagnosis, PGD can identify gene disorders before embryo transfer

At Dallas IVF, our fertility specialists know being proactive can increase pregnancy success. One preventive measure we take at our Dallas fertility center is using an advanced lab technique called preimplantation genetic diagnosis, PGD. When used with IVF, this technique can help couples who are carriers of a genetic disorder have a healthy baby.

PGD can identify healthy embryos prior to transfer to promote a successful pregnancy

Preimplantation genetic diagnosis is a form of chromosomal testing that allows fertility specialists to select and transfer unaffected embryos in order to prevent passing inheritable diseases to your children.

Many couples know that they are at risk for a genetic disorder because one partner has the disease or is a carrier. However, some patients of our Dallas fertility center are asymptomatic carriers, and they have no idea that they are at risk for passing a genetic disorder to their children. For this reason, preconception genetic testing and it can be important tests for couples trying to conceive.

The laboratory technique for PGD is similar to preimplantation genetic screening, PGS

Our Dallas fertility center performs both PGS and PGD. These tests involve screening for abnormal embryos during an IVF cycle. However, PGS can only tell if an embryo has an abnormal number of chromosomes. It cannot identify specific diseases. In contrast, PGD can diagnose specific genetic conditions. The vast majority of the time when PGD is performed at Dallas IVF, PGS is used simultaneously to gather as much genetic information on the embryo as possible.

  • The first step requires a couple to provide a blood or saliva sample to look for the presence or absence of a gene associated with a specific genetic disease.
  • If the test finds that one or both partners carry an abnormal gene, our reference genetics lab will look at 6-8 cells from an advanced-stage embryo to identify those embryos that carry the affected genetic material.
  • We only transfer unaffected embryos during IVF.

We perform PGD for the most common genetic disorders – cystic fibrosis, Fragile X and sickle cell disease – but we can use genetic testing address many different genetic diseases.

PGD is just one tool available at our Dallas fertility center that can help you have a healthy baby. If you’d like more information about PGD or PGS, please contact Dallas IVF today.

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